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M Laakso Selected Research

HDL Cholesterol

2/2013Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes.
8/2011High-density lipoprotein-cholesterol and not HbA1c was directly related to cardiovascular outcome in PROactive.
11/2005Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial.
2/2005The G-250A substitution in the promoter region of the hepatic lipase gene is associated with the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial.
10/2003The effects of the Pro12Ala polymorphism of the PPARgamma-2 gene on lipid metabolism interact with body size at birth.
4/2002Variation in the fatty acid binding protein 2 gene is not associated with markers of metabolic syndrome in patients with coronary heart disease.
8/2001Cardiovascular risk factors associated with insulin resistance cluster in families with early-onset coronary heart disease.
3/2001Cardiovascular disease in type 2 diabetes: challenge for treatment and prevention.
8/2000The Pro12A1a substitution in the peroxisome proliferator activated receptor gamma 2 is associated with an insulin-sensitive phenotype in families with familial combined hyperlipidemia and in nondiabetic elderly subjects with dyslipidemia.
6/2000MspI polymorphism at +83 bp in intron 1 of the human apolipoprotein A1 gene is associated with elevated levels of HDL cholesterol and apolipoprotein A1 in nondiabetic subjects but not in type 2 diabetic patients with coronary heart disease.

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M Laakso Research Topics

Disease

39Type 2 Diabetes Mellitus (MODY)
01/2021 - 01/2000
34Insulin Resistance
01/2021 - 01/2000
12Glucose Intolerance
12/2012 - 12/2000
7Obesity
05/2015 - 03/2001
7Coronary Disease (Coronary Heart Disease)
04/2002 - 01/2000
6Hyperinsulinism (Hyperinsulinemia)
12/2005 - 01/2000
6Dyslipidemias (Dyslipidemia)
10/2003 - 01/2000
5Familial Combined Hyperlipidemia (Combined Hyperlipidemia, Familial)
10/2001 - 01/2000
4Stroke (Strokes)
08/2011 - 02/2000
4Alzheimer Disease (Alzheimer's Disease)
05/2008 - 11/2000
4Body Weight (Weight, Body)
10/2005 - 04/2001
4Hypertension (High Blood Pressure)
06/2004 - 10/2000
3Myocardial Infarction
08/2011 - 07/2001
3Metabolic Syndrome (Dysmetabolic Syndrome X)
06/2008 - 04/2002
3Atherosclerosis
07/2007 - 09/2001
3Cardiovascular Diseases (Cardiovascular Disease)
09/2006 - 06/2004
3Albuminuria
11/2005 - 07/2002
3Body Weight Changes
10/2004 - 04/2000
3Congenital Hyperinsulinism
02/2003 - 10/2000
3Coronary Artery Disease (Coronary Atherosclerosis)
07/2002 - 04/2001
3Abdominal Obesity
06/2002 - 03/2001
2Overweight
11/2010 - 05/2004
2Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy)
09/2006 - 01/2004
1Neoplasms (Cancer)
03/2016
1Weight Loss (Weight Reduction)
09/2012
1Disorders of Excessive Somnolence (Hypersomnia)
07/2010
1Joint Diseases (Joint Disease)
07/2010
1Inflammation (Inflammations)
07/2008
1Necrosis
08/2007
1Heart Failure
09/2006
1Communication Disorders (Communication Disorder)
09/2006
1Breast Neoplasms (Breast Cancer)
09/2006
1Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
04/2006
1Proteinuria
01/2006

Drug/Important Bio-Agent (IBA)

29Glucose (Dextrose)FDA LinkGeneric
01/2021 - 01/2000
27Insulin (Novolin)FDA Link
01/2021 - 01/2000
16Triglycerides (Triacylglycerol)IBA
08/2011 - 01/2000
12LipidsIBA
05/2015 - 02/2000
10HDL CholesterolIBA
02/2013 - 06/2000
8CholesterolIBA
06/2008 - 01/2000
6HDL LipoproteinsIBA
08/2011 - 07/2000
5Proteins (Proteins, Gene)FDA Link
05/2008 - 10/2000
4PPAR gammaIBA
12/2004 - 08/2000
3Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
03/2016 - 10/2000
3Pioglitazone (Actos)FDA Link
08/2011 - 08/2005
3Lipoproteins (Lipoprotein)IBA
03/2011 - 08/2000
3C-Reactive ProteinIBA
07/2008 - 08/2007
3AcarboseFDA LinkGeneric
02/2005 - 06/2004
3oxidized low density lipoproteinIBA
10/2003 - 10/2000
3LDL Lipoproteins (beta Lipoproteins)IBA
10/2003 - 10/2000
2C-PeptideIBA
01/2021 - 10/2000
2Hepatocyte Nuclear FactorsIBA
01/2011 - 10/2000
2Transcription Factors (Transcription Factor)IBA
01/2011 - 06/2007
2Interleukin-6 (Interleukin 6)IBA
11/2010 - 08/2007
2Interleukin-1 Receptors (Interleukin 1 Receptor)IBA
07/2008 - 06/2008
2AdiponectinIBA
07/2008 - 06/2008
2Pharmaceutical PreparationsIBA
04/2008 - 09/2006
22,4-thiazolidinedione (thiazolidinedione)IBA
04/2008 - 09/2006
2Advanced Glycation End ProductsIBA
07/2007 - 06/2000
2TropomyosinIBA
09/2006 - 01/2004
2Blood Glucose (Blood Sugar)IBA
08/2005 - 07/2002
2Lipase (Acid Lipase)FDA Link
02/2005 - 07/2000
2EnzymesIBA
02/2005 - 02/2000
2Peroxisome Proliferator-Activated Receptors (PPAR)IBA
12/2004 - 10/2002
2Uncoupling Protein 1IBA
10/2004 - 04/2000
2KATP ChannelsIBA
02/2003 - 10/2002
2Adenosine Triphosphate (ATP)IBA
02/2003 - 10/2002
2ApolipoproteinsIBA
12/2001 - 11/2000
2Amino AcidsFDA Link
11/2001 - 01/2000
2Antihypertensive Agents (Antihypertensives)IBA
09/2001 - 12/2000
2VLDL LipoproteinsIBA
08/2001 - 10/2000
2Sulfonylurea ReceptorsIBA
10/2000 - 01/2000
2Apolipoprotein A-I (Apolipoprotein A1)IBA
10/2000 - 06/2000
2Leucine (L-Leucine)FDA Link
06/2000 - 01/2000
2preproneuropeptide YIBA
06/2000 - 01/2000
2Neuropeptide YIBA
06/2000 - 01/2000
2Proline (L-Proline)FDA Link
06/2000 - 01/2000
1Phosphatidylinositols (Phosphatidylinositol)IBA
03/2016
1Protein Kinases (Protein Kinase)IBA
03/2016
1Phosphotransferases (Kinase)IBA
06/2012
1Antidepressive Agents (Antidepressants)IBA
07/2010
1Interleukin-1 (Interleukin 1)IBA
07/2008
1A 19IBA
05/2008
1Sirtuin 1IBA
05/2008
1zinc-binding protein (zinc binding protein)IBA
05/2008
1Messenger RNA (mRNA)IBA
04/2008
1Retinol-Binding Proteins (Retinoid Binding Proteins)IBA
04/2008
1Glucagon-Like Peptide 1 (GLP 1)IBA
03/2008
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
08/2007
1Rosiglitazone (Avandia)FDA Link
09/2006
1Collagen Type III (Type III Collagen)IBA
09/2006
1GadoliniumIBA
09/2006
1DNA ProbesIBA
09/2006
1GhrelinIBA
06/2006
1Lamin Type A (Lamin A)IBA
04/2006
1Fenofibrate (CiL)FDA LinkGeneric
11/2005
1Fibric Acids (Fibrates)IBA
11/2005

Therapy/Procedure

4Therapeutics
11/2005 - 09/2001
1Gastric Bypass (Roux-en-Y Gastric Bypass)
09/2012
1Lasers (Laser)
11/2005